Description

cis-tert-Butyl 3-(4-Bromophenyl)Aziridine-2-Carboxylate is a high-value, chiral aziridine building block used in advanced organic synthesis. This compound is critical for introducing the strained, three-membered aziridine ring into target molecules, enabling the construction of complex nitrogen-containing structures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of novel drug candidates, particularly in protease inhibitor and antibiotic research.
• Agrochemical Synthesis: Building block for creating new herbicides, fungicides, and insecticides with enhanced activity and selectivity.
• Ligand and Catalyst Development: Precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Used in the synthesis of specialized polymers and functional materials with unique properties.
• Academic & R&D Laboratories: Essential reagent for methodological studies in organic chemistry, including ring-opening and cross-coupling reactions.
• Custom Synthesis: Serves as a starting point for contract research organizations (CROs) and CDMOs producing bespoke fine chemicals for clients.

Basic Information

Product Name	cis-tert-Butyl 3-(4-Bromophenyl)Aziridine-2-Carboxylate
CAS No.	1431365-58-0
Molecular Formula	C13H16BrNO2
Molecular Weight	298.18 g/mol
Synonyms	tert-Butyl (2R,3S)-3-(4-bromophenyl)aziridine-2-carboxylate; (2R,3S)-tert-Butyl 3-(4-bromophenyl)aziridine-2-carboxylate; 1,1-Dimethylethyl (2R,3S)-3-(4-bromophenyl)-2-aziridinecarboxylate; cis-3-(4-Bromophenyl)aziridine-2-carboxylic acid tert-butyl ester; Aziridine-2-carboxylic acid, 3-(4-bromophenyl)-, 1,1-dimethylethyl ester, (2R,3S)-; BOC-Aziridine Bromophenyl derivative
EINECS	Contact for details

Quality Control

Our cis-tert-Butyl 3-(4-Bromophenyl)Aziridine-2-Carboxylate is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and NMR for structural confirmation, to ensure compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and chiral purity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided. Keep container tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.