Description

2-Cyclopropyl-3-Methylpyridine-5-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyridine core substituted with a cyclopropyl and an aldehyde functional group. This compound is of significant value in modern organic synthesis, serving as a critical building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials and functional polymers due to its electron-deficient pyridine ring and reactive aldehyde group.
• Custom Synthesis and Contract Manufacturing: An essential building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Cyclopropyl-3-Methylpyridine-5-Carbaldehyde
CAS No.	1428234-66-5
Molecular Formula	C10H11NO
Molecular Weight	161.20 g/mol
Synonyms	5-Formyl-2-cyclopropyl-3-methylpyridine; 3-Methyl-2-cyclopropylpyridine-5-carboxaldehyde; 2-Cyclopropyl-3-methyl-5-pyridinecarboxaldehyde; 2-Cyclopropyl-3-picoline-5-carbaldehyde; Pyridine, 2-cyclopropyl-3-methyl-5-formyl-; 5-Aldehyde-2-cyclopropyl-3-methylpyridine
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our chemical intermediates. Production of 2-Cyclopropyl-3-Methylpyridine-5-Carbaldehyde adheres to current Good Manufacturing Practices (cGMP) where applicable, ensuring batch-to-batch consistency and reliability. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, available upon request. Our quality systems are designed to meet the exacting standards of pharmaceutical and advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.