Description

5-Ethoxy-3-(4-(trifluoromethoxy)phenyl)pyridine is a high-purity, advanced pharmaceutical intermediate with a distinct molecular architecture. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new compounds with specific biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging the trifluoromethoxy group for enhanced bioactivity and stability.
• Ligand & Catalyst Development: Serves as a sophisticated ligand scaffold in organometallic chemistry and catalysis for asymmetric synthesis.
• Material Science: A potential monomer or additive for creating specialty polymers with unique optical or electronic properties.
• Chemical Biology Probe: Utilized in academic and industrial research to study protein-ligand interactions and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic projects.

Basic Information

Product Name	5-Ethoxy-3-(4-(Trifluoromethoxy)Phenyl)Pyridine
CAS No.	1428234-57-4
Molecular Formula	C14H12F3NO2
Molecular Weight	283.25 g/mol
Synonyms	5-Ethoxy-3-[4-(trifluoromethoxy)phenyl]pyridine; 3-(4-Trifluoromethoxyphenyl)-5-ethoxypyridine; 5-Ethoxy-3-(4-trifluoromethoxyphenyl)pyridine; 1428234-57-4; 5-Ethoxy-3-(4-(trifluoromethoxy)phenyl)pyridine; Pyridine, 5-ethoxy-3-[4-(trifluoromethoxy)phenyl]-; 5-Ethoxy-3-(p-trifluoromethoxyphenyl)pyridine
EINECS	Contact for details

Quality Control

Our 5-Ethoxy-3-(4-(trifluoromethoxy)phenyl)pyridine is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.