Description

tert-Butyl 3-[(3-Bromopyridin-2-Yl)Oxy]Pyrrolidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new drugs, particularly in the areas of oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, especially kinase inhibitors and receptor modulators.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic molecules.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Employed in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.
• Agrochemical Intermediate: Potential use in the synthesis of novel crop protection agents and pesticides, leveraging its functionalized pyridine core.

Basic Information

Product Name	tert-Butyl 3-[(3-Bromopyridin-2-Yl)Oxy]Pyrrolidine-1-Carboxylate
CAS No.	1428233-84-4
Molecular Formula	C14H19BrN2O3
Molecular Weight	343.22 g/mol
Synonyms	1-Boc-3-[(3-bromopyridin-2-yl)oxy]pyrrolidine; 1-(tert-Butoxycarbonyl)-3-[(3-bromo-2-pyridinyl)oxy]pyrrolidine; tert-Butyl 3-((3-bromopyridin-2-yl)oxy)pyrrolidine-1-carboxylate; 3-[(3-Bromopyridin-2-yl)oxy]pyrrolidine-1-carboxylic acid tert-butyl ester; 1-Boc-3-(3-bromopyridin-2-yloxy)pyrrolidine; 1428233-84-4; Pyrrolidine-1-carboxylic acid, 3-[(3-bromo-2-pyridinyl)oxy]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-[(3-Bromopyridin-2-Yl)Oxy]Pyrrolidine-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory filings for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.