Description

Methyl 2-Chloro-6-(1,4-Diazepan-1-Yl)Isonicotinate is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound matters for its role in the synthesis of complex molecules with potential biological activity, particularly in medicinal chemistry research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its diazepane and chloropyridine motifs.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new active ingredients for crop protection.
• Chemical Biology Probes: Utilized in the development of tool compounds and probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized fine chemicals.

Basic Information

Product Name	Methyl 2-Chloro-6-(1,4-Diazepan-1-Yl)Isonicotinate
CAS No.	1427460-33-0
Molecular Formula	C12H16ClN3O2
Molecular Weight	269.73 g/mol
Synonyms	Methyl 2-chloro-6-(1,4-diazepan-1-yl)isonicotinate; 2-Chloro-6-(1,4-diazepan-1-yl)isonicotinic acid methyl ester; 1,4-Diazepane, 1-(2-chloro-6-(methoxycarbonyl)-4-pyridinyl)-; Methyl 2-chloro-6-(homopiperazinyl)isonicotinate; 2-Chloro-6-(homopiperazin-1-yl)isonicotinic acid methyl ester; 6-(1,4-Diazepan-1-yl)-2-chloroisonicotinic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-Chloro-6-(1,4-Diazepan-1-Yl)Isonicotinate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects with material meeting high-purity research grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended long-term storage at 2-8°C. The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.