Description

1,1-Dimethyl-2-Oxa-8-Aza-Spiro[4.5]Decane Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral research. It is essential for medicinal chemists and process development scientists in pharmaceutical R&D and fine chemical manufacturing seeking reliable, high-quality intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting neurological disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• Process Chemistry Development: Serves as a critical starting material for scaling up the production of target molecules under Good Manufacturing Practice (GMP) conditions.
• Active Pharmaceutical Ingredient (API) Synthesis: Incorporated into the final synthetic steps for producing specific APIs requiring its spirocyclic amine moiety.
• Bioconjugation & Probe Development: Potential use in creating chemical probes or conjugates for biochemical and diagnostic applications due to its reactive nitrogen center.

Basic Information

Product Name	1,1-Dimethyl-2-Oxa-8-Aza-Spiro[4.5]Decane Hydrochloride
CAS No.	1427425-91-9
Molecular Formula	C9H18ClNO
Molecular Weight	191.70 g/mol
Synonyms	1,1-Dimethyl-2-oxa-8-azaspiro[4.5]decane hydrochloride; 8-Aza-1,1-dimethyl-2-oxaspiro[4.5]decane hydrochloride; 2-Oxa-8-azaspiro[4.5]decane, 1,1-dimethyl-, hydrochloride; Spirocyclic amine hydrochloride; 1,1-Dimethyl-2-oxa-8-azaspiro[4.5]decane HCl
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized and controlled using advanced analytical techniques including HPLC, NMR, and mass spectrometry to guarantee identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are available upon request. We support development under quality systems suitable for use in GMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.