Description

Methyl 4-Bromo-2-Fluoro-6-Methoxybenzoate is a high-purity fluorinated and brominated benzoate ester, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its unique substitution pattern, which provides versatile reactivity for constructing complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those containing fluorinated and brominated aromatic systems.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the fluorine and bromine atoms enhance biological activity and stability.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and liquid crystals with specific electronic or optical properties.
• Chemical Biology & Probe Development: Utilized in creating molecular probes and tags for studying biological processes due to its halogen handles for further functionalization.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination, enabling rapid diversification of chemical space.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	Methyl 4-Bromo-2-Fluoro-6-Methoxybenzoate
CAS No.	1427415-25-5
Molecular Formula	C9H8BrFO3
Molecular Weight	263.06 g/mol
Synonyms	Benzoic acid, 4-bromo-2-fluoro-6-methoxy-, methyl ester; Methyl 4-bromo-2-fluoro-6-methoxybenzoate; 4-Bromo-2-fluoro-6-methoxybenzoic acid methyl ester; 2-Fluoro-4-bromo-6-methoxybenzoic acid methyl ester; Methyl 2-fluoro-4-bromo-6-methoxybenzoate
EINECS	Contact for details

Quality Control

Every batch of Methyl 4-Bromo-2-Fluoro-6-Methoxybenzoate is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards, and comprehensive analytical testing is performed to guarantee identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.