Description

Methyl 4-Bromo-2-Fluoro-6-Methylbenzoate is a high-purity, multi-functional halogenated benzoate ester serving as a critical building block in advanced organic synthesis. This compound is valued for its precise molecular architecture, which enables the introduction of both bromine and fluorine substituents in a single, controlled step. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, such as active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated and brominated drug candidates, particularly in kinase inhibitor and anti-inflammatory research.
• Agrochemical Synthesis: Used in the creation of novel herbicides and pesticides where the halogenated aromatic core provides specific biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for specialty monomers or ligands in the development of advanced polymers and metal-organic frameworks (MOFs).
• Chemical Biology: Employed as a probe or labeling reagent due to the reactivity of the bromine atom for further functionalization (e.g., Suzuki coupling).
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring a specific, halogenated benzoic acid derivative.

Basic Information

Product Name	Methyl 4-Bromo-2-Fluoro-6-Methylbenzoate
CAS No.	1427409-40-2
Molecular Formula	C9H8BrFO2
Molecular Weight	247.06 g/mol
Synonyms	4-Bromo-2-fluoro-6-methylbenzoic acid methyl ester; Methyl 4-bromo-2-fluoro-6-methylbenzoate; Benzoic acid, 4-bromo-2-fluoro-6-methyl-, methyl ester; 2-Fluoro-4-bromo-6-methylbenzoic acid methyl ester; Methyl 2-fluoro-4-bromo-6-methylbenzoate
EINECS	Contact for details

Quality Control

Our production of Methyl 4-Bromo-2-Fluoro-6-Methylbenzoate adheres to stringent internal quality standards to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.