Description

Methyl 4-Fluoro-3-Methoxyphenylacetate is a high-purity fluorinated aromatic ester building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules, particularly within the pharmaceutical and agrochemical sectors. It is needed by R&D chemists and process development scientists for constructing active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where the 4-fluoro-3-methoxyphenyl moiety is a critical structural feature.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides where fluorinated aromatic structures enhance biological activity and stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for fluorinated components in electronic display and lighting technologies.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, esterifications, and other transformations to introduce the fluorinated methoxyphenylacetate group.
• Flavor & Fragrance Intermediate: Potential use in the synthesis of complex aromatic compounds for specialty chemical applications.
• Academic & Contract Research: Valuable reagent for methodological development and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	Methyl 4-Fluoro-3-Methoxyphenylacetate
CAS No.	1427397-59-8
Molecular Formula	C10H11FO3
Molecular Weight	198.19 g/mol
Synonyms	Methyl (4-fluoro-3-methoxyphenyl)acetate; Acetic acid, 2-(4-fluoro-3-methoxyphenyl)-, methyl ester; 4-Fluoro-3-methoxybenzeneacetic acid methyl ester; Methyl 4-fluoro-3-methoxybenzeneacetate; Methyl 2-(4-fluoro-3-methoxyphenyl)acetate; 1427397-59-8; Methyl 4-Fluoro-3-Methoxyphenylacetate
EINECS	Contact for details

Quality Control

Our Methyl 4-Fluoro-3-Methoxyphenylacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.