Description

4-Bromo-2-Hydroxymethyl-Benzoic Acid Methyl Ester is a versatile brominated aromatic ester building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a reactive bromine atom and a hydroxymethyl group, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules with benzofuran or benzodioxole cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis.
• Material Science Research: Building block for organic semiconductors, liquid crystals, and advanced polymers.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific projects.

Basic Information

Item	Detail
Product Name	4-Bromo-2-Hydroxymethyl-Benzoic Acid Methyl Ester
CAS No.	1427385-26-9
Molecular Formula	C10H11BrO3
Molecular Weight	259.10 g/mol
Synonyms	Methyl 4-Bromo-2-(hydroxymethyl)benzoate; 4-Bromo-2-(hydroxymethyl)benzoic Acid Methyl Ester; 2-(Hydroxymethyl)-4-bromobenzoic Acid Methyl Ester; Benzoic acid, 4-bromo-2-(hydroxymethyl)-, methyl ester; Methyl 4-bromo-2-(hydroxymethyl)benzoate
EINECS	Contact for details

Quality Control

Our production of 4-Bromo-2-Hydroxymethyl-Benzoic Acid Methyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your critical syntheses. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and NMR for structural confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We operate under a cGMP-compliant quality management system suitable for supporting pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.