Description

1H-Indole-6-Carboxylic Acid, 7-Fluoro-, Methyl Ester is a high-purity fluorinated indole derivative, a crucial building block in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical synthon for the research and development of new drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators, leveraging the bioactivity of the fluorinated indole scaffold.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for electron-transport or emissive layer materials in electronic displays and lighting.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Biochemical Research: Used as a standard or probe in biochemical assays and proteomics research due to its specific fluorescent properties.
• Material Science: A building block for advanced polymers and functional materials with specific optical or electronic characteristics.

Basic Information

Product Name	1H-Indole-6-Carboxylic Acid, 7-Fluoro-, Methyl Ester
CAS No.	1427366-38-8
Molecular Formula	C10H8FNO2
Molecular Weight	193.17 g/mol
Synonyms	7-Fluoro-1H-indole-6-carboxylic acid methyl ester; Methyl 7-fluoro-1H-indole-6-carboxylate; 7-Fluoroindole-6-carboxylic Acid Methyl Ester; 1H-Indole-6-carboxylic acid, 7-fluoro-, methyl ester; 1427366-38-8; 7-Fluoro-6-(methoxycarbonyl)-1H-indole
EINECS	Contact for details

Quality Control

Our 1H-Indole-6-Carboxylic Acid, 7-Fluoro-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We can support development and commercial projects requiring compliance with cGMP, ICH Q7, and other relevant regulatory guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.