Description

1-Oxa-6-Azaspiro[3.3]Heptane Oxalate is a high-purity, advanced pharmaceutical intermediate and building block of significant interest in modern drug discovery. Its unique spirocyclic scaffold is highly valued for its three-dimensionality and potential to improve the physicochemical properties of drug candidates. This compound is primarily sought after by research and development teams in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially those targeting complex biological pathways.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization programs to explore structure-activity relationships (SAR) and improve drug-like properties.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a component for constructing linkers or warheads in bifunctional degrader molecules.
• CNS Drug Discovery: Employed in the research of therapeutics for neurological disorders due to its ability to cross the blood-brain barrier.
• Chemical Biology Tool: Utilized as a probe or labeled compound for studying enzyme function and biological mechanisms.
• Library Synthesis for High-Throughput Screening: A valuable scaffold for generating diverse compound libraries to identify new biological activity.

Basic Information

Item	Detail
Product Name	1-Oxa-6-Azaspiro[3.3]Heptane Oxalate
CAS No.	1427358-60-8
Molecular Formula	C8H11NO5
Molecular Weight	201.18 g/mol
Synonyms	1-Oxa-6-azaspiro[3.3]heptane oxalate salt; 6-Oxa-1-azaspiro[3.3]heptane oxalate; Oxaspiroheptane oxalate; 1-Oxa-6-azaspiro[3.3]heptane, oxalic acid salt; Spiro[3.3]heptane-1,6-oxazolidine oxalate; Azaspiroheptane oxalate; 6-Oxa-1-azaspiro[3.3]heptane ethanedioate
EINECS	Contact for details

Quality Control

Our 1-Oxa-6-Azaspiro[3.3]Heptane Oxalate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data, including HPLC purity, NMR, and MS confirmation. Our quality commitment supports cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong acids, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.