Description

Ethyl 2-(3-Bromo-2-Fluorophenyl)-2-Oxoacetate is a high-purity, specialized organic building block featuring a reactive α-ketoester functional group. This compound is of significant value in pharmaceutical and agrochemical research and development, serving as a versatile precursor for synthesizing complex molecules. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and advanced material sectors.

Application

• Pharmaceutical Intermediate: A key synthon for the construction of active pharmaceutical ingredients (APIs), particularly those containing fluorinated and brominated aromatic systems.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogenated phenyl ring.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands or organocatalysts in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials or advanced polymers where specific halogen and carbonyl functionalities are required.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.
• Academic and Industrial R&D: Utilized in exploratory chemistry for developing new synthetic methodologies and novel chemical entities.

Basic Information

Product Name	Ethyl 2-(3-Bromo-2-Fluorophenyl)-2-Oxoacetate
CAS No.	1426958-42-0
Molecular Formula	C10H8BrFO3
Molecular Weight	275.07 g/mol
Synonyms	Ethyl 3-Bromo-2-fluorobenzoylformate; 2-(3-Bromo-2-fluorophenyl)-2-oxoacetic acid ethyl ester; Ethyl (3-bromo-2-fluorobenzoyl)formate; α-Oxo-3-bromo-2-fluorobenzeneacetic acid ethyl ester; Ethyl α-oxo-3-bromo-2-fluorophenylacetate; 3-Bromo-2-fluorophenylglyoxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-(3-Bromo-2-Fluorophenyl)-2-Oxoacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.