Description

(1S,3R,7S,8S,8Ar)-1,2,3,7,8,8A-Hexahydro-3,7-Dimethyl-8-[2-[(2R)-Tetrahydro-4,6-Dioxo-2H-Pyran-2-Yl]Ethyl]-1-Naphthalenyl 2,2-Dimethylbutanoate CAS NO 1426939-44-7 is a high-purity, complex organic ester with a defined stereochemistry, making it a valuable advanced pharmaceutical intermediate or building block for sophisticated chemical synthesis. Its precise molecular architecture is critical for researchers and manufacturers requiring chirally pure compounds in the development of active pharmaceutical ingredients (APIs) and other fine chemicals. This product is essential for R&D laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical sectors seeking reliable, high-quality intermediates for complex synthetic pathways.

Application

• Pharmaceutical Intermediate: Key chiral building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs), particularly for complex therapeutic agents.
• Agrochemical Research: Used in the development of advanced, stereospecific pesticides, herbicides, and plant growth regulators.
• Fine Chemical Synthesis: Serves as a precursor for synthesizing complex esters, lactones, and other specialty organic compounds in research and development.
• Academic & Industrial R&D: A valuable reference standard and starting material for methodological studies in organic chemistry, asymmetric synthesis, and catalysis.
• Material Science: Potential monomer or additive in the research of specialized polymers with tailored properties.

Basic Information

Item	Details
Product Name	(1S,3R,7S,8S,8Ar)-1,2,3,7,8,8A-Hexahydro-3,7-Dimethyl-8-[2-[(2R)-Tetrahydro-4,6-Dioxo-2H-Pyran-2-Yl]Ethyl]-1-Naphthalenyl 2,2-Dimethylbutanoate
CAS No.	1426939-44-7
Molecular Formula	C25H36O5
Molecular Weight	416.55 g/mol
Synonyms	2,2-Dimethylbutanoic acid (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R)-4,6-dioxotetrahydro-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester; (8S,8aR)-8-[2-[(2R)-4,6-Dioxotetrahydro-2H-pyran-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-1-naphthalenyl 2,2-dimethylbutanoate; Pivalic acid derivative of a hexahydronaphthalene-dihydropyrandione conjugate; Complex Dihydropyrandione Ester; Chiral Lactone Ester Intermediate.
EINECS	Contact for details

Quality Control

Our production of this high-purity intermediate adheres to stringent quality protocols. Every batch undergoes comprehensive analytical testing, including HPLC for assay and purity, chiral analysis to confirm stereochemical integrity, and identification via NMR and IR spectroscopy. We provide detailed Certificates of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or cGMP-grade specifications. Our quality management system is designed to meet the exacting standards of the pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept in a well-ventilated area and protected from moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.