Description

Methyl 2-{[(tert-Butoxy)Carbonyl]Amino}Cyclopropane-1-Carboxylate is a high-purity, protected amino acid derivative featuring a cyclopropane ring, a key structural motif in medicinal chemistry. This compound serves as a versatile and critical building block for the synthesis of complex molecules, particularly in pharmaceutical research and development. It is essential for chemists and researchers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-quality intermediates for constructing novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, antiviral agents, and enzyme inhibitors.
• Peptidomimetics & Constrained Peptides: Used to introduce the rigid cyclopropane scaffold into peptide backbones, enhancing metabolic stability and biological activity.
• Agrochemical Research: Serves as a building block for developing new generation herbicides, fungicides, and insecticides with unique modes of action.
• Chemical Biology Probes: Utilized in the creation of labeled compounds and activity-based probes for studying enzyme function and biological pathways.
• Material Science: Potential monomer or additive for creating specialized polymers with tailored thermal or mechanical properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects requiring high-fidelity chiral intermediates.

Basic Information

Product Name	Methyl 2-{[(tert-Butoxy)Carbonyl]Amino}Cyclopropane-1-Carboxylate
CAS No.	1426414-00-7
Molecular Formula	C11H19NO4
Molecular Weight	229.27 g/mol
Synonyms	1-Methyl 2-[(tert-butoxycarbonyl)amino]cyclopropane-1-carboxylate; Boc-ACPC-OMe; (1R,2S)-Methyl 2-[(tert-butoxycarbonyl)amino]cyclopropanecarboxylate (for chiral form); (1S,2R)-Methyl 2-[(tert-butoxycarbonyl)amino]cyclopropanecarboxylate (for chiral form); Methyl 2-(Boc-amino)cyclopropanecarboxylate; 2-[(tert-Butoxycarbonyl)amino]cyclopropanecarboxylic acid methyl ester; Boc-Amino Cyclopropane Carboxylic Acid Methyl Ester; N-Boc-1-Amino-2-carbomethoxycyclopropane
EINECS	Contact for details

Quality Control

Every batch of Methyl 2-{[(tert-Butoxy)Carbonyl]Amino}Cyclopropane-1-Carboxylate is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure compliance with exacting purity standards suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.