Description

tert-Butyl 2-[3-Chloro-5-(Trifluoromethyl)-2-Pyridyl]-2-Cyanoacetate CAS NO 1426290-06-3 is a high-value, multi-functional chemical intermediate characterized by its pyridine core and cyanoacetate ester functionality. This compound is essential for the synthesis of complex molecules, particularly in the development of advanced agrochemicals and pharmaceuticals, where its unique halogenated and trifluoromethylated structure enables precise bioactivity. It is primarily sought after by research and development teams, process chemists, and manufacturers in the agrochemical and pharmaceutical industries for creating novel active ingredients.

Application

• Agrochemical Intermediate: A key building block in the synthesis of next-generation herbicides, insecticides, and fungicides, leveraging the pyridine and trifluoromethyl motifs for enhanced efficacy and environmental profile.
• Pharmaceutical Intermediate: Used in the research and production of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and other therapeutic areas.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of advanced organic materials, including liquid crystals and functional polymers, due to its rigid aromatic structure.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and contract research organizations (CROs/CMOs) developing proprietary compounds.

Basic Information

Product Name	tert-Butyl 2-[3-Chloro-5-(Trifluoromethyl)-2-Pyridyl]-2-Cyanoacetate
CAS No.	1426290-06-3
Molecular Formula	C13H12ClF3N2O2
Molecular Weight	320.69 g/mol
Synonyms	tert-Butyl (3-chloro-5-(trifluoromethyl)pyridin-2-yl)cyanoacetate; 2-Cyano-2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)acetic acid tert-butyl ester; 2-Pyridineacetic acid, 2-cyano-α-(3-chloro-5-(trifluoromethyl)-2-pyridinyl)-, 1,1-dimethylethyl ester; tert-Butyl (3-chloro-5-(trifluoromethyl)picolinyl)cyanoacetate; 1426290-06-3; CAS 1426290-06-3
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-[3-Chloro-5-(Trifluoromethyl)-2-Pyridyl]-2-Cyanoacetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.