Description

7-Bromo-5-Chloro-1-Methyl-1H-Pyrazolo[4,3-B]Pyridine is a high-value, multi-halogenated pyrazolopyridine derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in providing a versatile, functionalized scaffold for constructing complex molecular architectures, particularly in pharmaceutical discovery. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients. The precise bromo and chloro substitutions on the fused heterocyclic system make it a key building block for targeted synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive heterocyclic core.
• Material Science: Serves as a building block for creating specialized organic electronic materials and ligands for catalysis.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biological target validation.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploratory synthesis projects.
• Custom Synthesis: Acts as a starting material for contract manufacturing organizations (CMOs) producing bespoke fine chemicals for clients.

Basic Information

Product Name	7-Bromo-5-Chloro-1-Methyl-1H-Pyrazolo[4,3-B]Pyridine
CAS No.	1426254-96-7
Molecular Formula	C7H5BrClN3
Molecular Weight	262.49 g/mol
Synonyms	1-Methyl-7-bromo-5-chloro-1H-pyrazolo[4,3-b]pyridine; 7-Bromo-5-chloro-1-methyl-1H-pyrazolo[4,3-b]pyridine; 1H-Pyrazolo[4,3-b]pyridine, 7-bromo-5-chloro-1-methyl-; 1426254-96-7; 5-Chloro-7-bromo-1-methyl-1H-pyrazolo[4,3-b]pyridine; 1-Methyl-5-chloro-7-bromo-1H-pyrazolo[4,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 7-Bromo-5-Chloro-1-Methyl-1H-Pyrazolo[4,3-B]Pyridine is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality ensures the material meets the high standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.