Description

Methyl 1-Ethynylcyclopropanecarboxylate is a high-value, multifunctional chemical building block featuring both a cyclopropane ring and a terminal alkyne group. This unique structural motif makes it a critical intermediate for the synthesis of complex molecules in advanced research and development. It is primarily sought after by pharmaceutical, agrochemical, and advanced materials chemists for constructing novel molecular architectures. The compound with CAS number 1423705-50-3 is supplied to meet the stringent demands of process chemistry and discovery laboratories.

Application

This versatile synthon is employed in various sophisticated chemical transformations, including:

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring strained ring systems or alkyne handles for click chemistry.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the cyclopropane moiety can enhance biological activity.
• Material Science: Acts as a monomer or cross-linking agent in the development of specialty polymers and advanced materials with tailored properties.
• Organic Synthesis Building Block: Utilized in [3+2] cycloadditions, Sonogashira couplings, and other metal-catalyzed reactions to introduce functionalized cyclopropane units.
• Ligand and Catalyst Development: Provides a scaffold for creating novel ligands used in asymmetric catalysis and organometallic chemistry.

Basic Information

Product Name	Methyl 1-Ethynylcyclopropanecarboxylate
CAS No.	1423705-50-3
Molecular Formula	C7H8O2
Molecular Weight	124.14 g/mol
Synonyms	1-Ethynylcyclopropanecarboxylic acid methyl ester; Methyl 1-ethynylcyclopropane-1-carboxylate; Cyclopropanecarboxylic acid, 1-ethynyl-, methyl ester; 1-(Methoxycarbonyl)cyclopropylacetylene
EINECS	Contact for details

Quality Control

Our Methyl 1-Ethynylcyclopropanecarboxylate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to the reactive alkyne functionality, it is recommended to store under an inert atmosphere for long-term stability and to minimize moisture uptake.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.