Description

Sulfo-Cyanine7 Maleimide is a near-infrared (NIR) fluorescent dye derivative designed for site-specific bioconjugation. This water-soluble, sulfonated cyanine dye is essential for creating stable, bright fluorescent probes for advanced bioimaging and diagnostic applications. It is primarily used by researchers and manufacturers in the biopharmaceutical, diagnostic, and life science sectors for labeling proteins, antibodies, and other biomolecules via thiol-maleimide chemistry.

Application

• Antibody-Drug Conjugate (ADC) Development: Site-specific conjugation of cytotoxic payloads or imaging agents to monoclonal antibodies.
• In Vivo Imaging Probes: Labeling peptides, proteins, or nanoparticles for deep-tissue fluorescence imaging in preclinical research.
• Diagnostic Assay Reagents: Conjugation to detection antibodies or proteins for fluorescence-based immunoassays (e.g., ELISA, lateral flow).
• Protein Labeling & Tracking: Covalent attachment to engineered cysteine residues for studying protein dynamics, localization, and interactions.
• Flow Cytometry Reagents: Creating bright, photostable fluorescent conjugates for cell surface marker detection.
• Nucleic Acid Probes: Conjugation to thiol-modified oligonucleotides for fluorescence in situ hybridization (FISH) and other genomic techniques.

Basic Information

Product Name	Sulfo-Cyanine7 Maleimide
CAS No.	1422279-40-0
Molecular Formula	C45H49KN2O11S3
Molecular Weight	937.19 g/mol
Synonyms	Sulfo-Cy7 Maleimide; Sulfo Cyanine7 Maleimide; Cy7 Sulfo Maleimide; Maleimide-functionalized Sulfo-Cyanine7; 2-[(1E,3E)-5-[5-(1-Carboxy-3-sulfo-propyl)-3,3-dimethyl-1-(3-sulfo-propyl)-1,3-dihydro-indol-2-ylidene]-penta-1,3-dienyl]-3,3-dimethyl-1-(3-sulfo-propyl)-3H-indolium-5-carboxylic acid maleimide; Sulfo-Cy7 Mal; NIR-797 Maleimide derivative
EINECS	Contact for details

Quality Control

Every batch of Sulfo-Cyanine7 Maleimide is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure high purity and consistent performance for critical research and development applications. A detailed Certificate of Analysis (COA) providing purity (HPLC), identity (MS, NMR), and functional performance data is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	Dark green to blue-green solid
Identification (HPLC-MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Absorption (λmax)	747 nm ± 5 nm
Emission (λmax)	774 nm ± 5 nm
Extinction Coefficient (ε)	≥ 199,000 cm⁻¹M⁻¹
Water Content (KF)	≤ 5.0%
Functional Performance	Conjugates efficiently with thiols

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.