Description

1-(2-Methoxyethyl)-1,8-Diazaspiro[4.5]Decan-2-One is a high-purity, advanced pharmaceutical intermediate belonging to the diazaspirocyclic chemical class. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily sought by pharmaceutical R&D departments and fine chemical manufacturers engaged in developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new drug candidates, especially for neurological and psychiatric disorders.
• API Synthesis: Used in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs) targeting specific biological pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the production of clinical trial materials and commercial APIs.
• Biochemical Research: Employed in academic and industrial research to study enzyme inhibition and receptor binding activities.

Basic Information

Product Name	1-(2-Methoxyethyl)-1,8-Diazaspiro[4.5]Decan-2-One
CAS No.	1422140-97-3
Molecular Formula	C12H22N2O2
Molecular Weight	226.32 g/mol
Synonyms	1-(2-Methoxyethyl)-1,8-diazaspiro[4.5]decan-2-one; 1,8-Diazaspiro[4.5]decan-2-one, 1-(2-methoxyethyl)-; UNII-2K4J6Q8K8F; 2K4J6Q8K8F; 1-(2-Methoxy-ethyl)-1,8-diaza-spiro[4.5]decan-2-one; 1-(2-Methoxyethyl)-1,8-diazaspiro[4.5]decan-2-one (CAS 1422140-97-3)
EINECS	Contact for details

Quality Control

Our 1-(2-Methoxyethyl)-1,8-Diazaspiro[4.5]Decan-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.