Description

3-(4-(Cyclopropylmethyl)-1-Isopropylpiperazin-2-Yl)-[1,2,4]Triazolo[4,3-A]Pyridine-6-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical companies, contract research organizations (CROs), and academic institutions engaged in drug discovery programs targeting central nervous system (CNS) and other therapeutic areas.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for CNS-targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes.
• API Development: Serves as a precursor in the development and scale-up of new active pharmaceutical ingredients.
• Biochemical Research: Potential tool compound for investigating specific biological pathways and receptor interactions.
• Contract Manufacturing: Supplied to CDMOs for the production of clinical trial materials and commercial APIs.

Basic Information

Product Name	3-(4-(Cyclopropylmethyl)-1-Isopropylpiperazin-2-Yl)-[1,2,4]Triazolo[4,3-A]Pyridine-6-Carboxylic Acid
CAS No.	1422134-99-3
Molecular Formula	C20H25N5O2
Molecular Weight	367.45 g/mol
Synonyms	3-[4-(Cyclopropylmethyl)-1-isopropylpiperazin-2-yl]-[1,2,4]triazolo[4,3-a]pyridine-6-carboxylic acid; 3-(4-(Cyclopropylmethyl)-1-isopropyl-2-piperazinyl)-[1,2,4]triazolo[4,3-a]pyridine-6-carboxylic acid; [1,2,4]Triazolo[4,3-a]pyridine-6-carboxylic acid, 3-[4-(cyclopropylmethyl)-1-(1-methylethyl)-2-piperazinyl]-; 1422134-99-3; 3-(4-(Cyclopropylmethyl)-1-isopropylpiperazin-2-yl)-[1,2,4]triazolo[4,3-a]pyridine-6-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-(4-(Cyclopropylmethyl)-1-Isopropylpiperazin-2-Yl)-[1,2,4]Triazolo[4,3-A]Pyridine-6-Carboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supported by a detailed Certificate of Analysis (COA). We adhere to ICH guidelines for stability and impurity profiling, ensuring the material meets the stringent requirements for pharmaceutical R&D and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is stable under these conditions but should be handled in accordance with good laboratory practices for light-sensitive materials. Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.