Description

2-((2-Methylthiazol-4-Yl)Methyl)-2,7-Diazaspiro[4.4]Nonan-3-One is a high-value, advanced pharmaceutical intermediate featuring a unique spirocyclic and diaza-thiazole hybrid structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel bioactive molecules targeting central nervous system (CNS) and other therapeutic areas. It is primarily sought after by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in the development of new drug candidates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in CNS and neurological disorder research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its spirocyclic and heterocyclic framework.
• Protease Inhibitor Development: Potential scaffold for the development of enzyme inhibitors, leveraging the 2,7-diazaspiro[4.4]nonane core.
• Chemical Biology Probes: Serves as a precursor for creating molecular probes to study biological pathways and protein functions.
• High-Throughput Screening Libraries: Incorporated into diverse compound libraries for biological screening against various disease targets.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	2-((2-Methylthiazol-4-Yl)Methyl)-2,7-Diazaspiro[4.4]Nonan-3-One
CAS No.	1422134-56-2
Molecular Formula	C12H17N3OS
Molecular Weight	251.35 g/mol
Synonyms	2,7-Diazaspiro[4.4]nonan-3-one, 2-[(2-methyl-4-thiazolyl)methyl]-; 2-((2-Methyl-1,3-thiazol-4-yl)methyl)-2,7-diazaspiro[4.4]nonan-3-one; 2-[(2-Methylthiazol-4-yl)methyl]-2,7-diazaspiro[4.4]nonan-3-one; UNII-9V2F8W8K3T; 9V2F8W8K3T; Spiro[4.4]nonane-2,7-diazine derivative; Thiazole-spirocyclic amine conjugate
EINECS	Contact for details

Quality Control

Our 2-((2-Methylthiazol-4-Yl)Methyl)-2,7-Diazaspiro[4.4]Nonan-3-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if possible to maximize shelf life.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.