Description

2-(Cyclopropylmethyl)-2,7-Diazaspiro[4.5]Decan-1-One is a high-purity, advanced pharmaceutical intermediate belonging to the diazaspirodecane class of heterocyclic compounds. This compound is of significant commercial value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily needed by pharmaceutical R&D laboratories, contract development and manufacturing organizations (CDMOs), and fine chemical suppliers engaged in the development of next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates targeting neurological disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• API Synthesis: Used in the development and scale-up of Active Pharmaceutical Ingredients (APIs), especially those with spirocyclic and bridged ring systems.
• CNS Drug Development: Employed in the research of potential treatments for conditions such as depression, anxiety, and schizophrenia due to its privileged structure.
• Oncological Therapeutics: Investigated as a building block for small molecule inhibitors and targeted cancer therapies.
• Contract Manufacturing: Supplied to CDMOs for custom synthesis and process development under cGMP guidelines.

Basic Information

Product Name	2-(Cyclopropylmethyl)-2,7-Diazaspiro[4.5]Decan-1-One
CAS No.	1422069-83-7
Molecular Formula	C13H22N2O
Molecular Weight	222.33 g/mol
Synonyms	2-(Cyclopropylmethyl)-2,7-diazaspiro[4.5]decan-1-one; 2,7-Diazaspiro[4.5]decan-1-one, 2-(cyclopropylmethyl)-; UNII-7K8L9F2F1I; 7K8L9F2F1I; 2-Cyclopropylmethyl-2,7-diazaspiro[4.5]decan-1-one; 2-(Cyclopropylmethyl)-2,7-diazaspiro[4.5]decan-1-one (CAS 1422069-83-7); 2-(Cyclopropylmethyl)-2,7-diazaspiro[4.5]decanone
EINECS	Contact for details

Quality Control

Our 2-(Cyclopropylmethyl)-2,7-Diazaspiro[4.5]Decan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay (HPLC), related substances, and residual solvents. Our quality commitment aligns with ICH guidelines, and we support development under cGMP standards for advanced clinical phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; therefore, containers should be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.