Description

Rel-(1S,5S)-1-(Allyloxymethyl)-6-Oxa-9-Azaspiro[4.5]Decane CAS NO 1422067-74-0 is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic and heterocyclic structure. This compound is of significant value for its role as a key chiral building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral research. It is primarily needed by pharmaceutical R&D laboratories, process chemistry teams, and fine chemical manufacturers engaged in the development of complex, stereochemically defined drug candidates.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new drug candidates, especially those targeting neurological disorders.
• API Synthesis: Serves as a key building block in multi-step synthetic routes for complex Active Pharmaceutical Ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its unique spirocyclic scaffold.
• Process Development: Employed in scaling up synthetic pathways from laboratory to pilot and commercial production scales.
• Asymmetric Synthesis: Utilized in reactions requiring high stereochemical control to introduce specific chiral centers into target molecules.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	Rel-(1S,5S)-1-(Allyloxymethyl)-6-Oxa-9-Azaspiro[4.5]Decane
CAS No.	1422067-74-0
Molecular Formula	C12H21NO2
Molecular Weight	211.30 g/mol
Synonyms	1-(Allyloxymethyl)-6-oxa-9-azaspiro[4.5]decane (rel-(1S,5S)-); 6-Oxa-9-azaspiro[4.5]decane, 1-(2-propen-1-yloxymethyl)-, (1S,5S)-rel-; (1S,5S)-rel-1-[(Allyloxy)methyl]-6-oxa-9-azaspiro[4.5]decane; Allyloxymethyl-6-oxa-9-azaspiro[4.5]decane; Spirocyclic oxazolidine intermediate; CAS 1422067-74-0
EINECS	Contact for details

Quality Control

Our Rel-(1S,5S)-1-(Allyloxymethyl)-6-Oxa-9-Azaspiro[4.5]Decane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.