Description

2-(Pyridin-3-Ylmethyl)-2,8-Diazaspiro[4.5]Decan-1-One is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic and diaza scaffold. This compound is of significant value in medicinal chemistry for its role as a key building block in the research and development of novel therapeutic agents. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of complex molecules targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for CNS-targeting drugs.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its privileged spirocyclic structure.
• Preclinical Drug Development: Serves as a key precursor in the scale-up synthesis of candidate compounds for toxicology and pharmacokinetic studies.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening against various biological targets.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	2-(Pyridin-3-Ylmethyl)-2,8-Diazaspiro[4.5]Decan-1-One
CAS No.	1422063-40-8
Molecular Formula	C15H21N3O
Molecular Weight	259.35 g/mol
Synonyms	2,8-Diazaspiro[4.5]decan-1-one, 2-[(3-pyridinyl)methyl]-; 2-((Pyridin-3-yl)methyl)-2,8-diazaspiro[4.5]decan-1-one; 3-((1-Oxo-2,8-diazaspiro[4.5]decan-2-yl)methyl)pyridine; 2-(3-Pyridylmethyl)-2,8-diazaspiro[4.5]decan-1-one; 2-(Pyridin-3-ylmethyl)-2,8-diazaspiro[4.5]decan-1-one; Spirocyclic diaza compound 1422063-40-8
EINECS	Contact for details

Quality Control

Our 2-(Pyridin-3-Ylmethyl)-2,8-Diazaspiro[4.5]Decan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.