Description

5-(Pyridin-3-Yl)-2,3-Dihydrospiro[Indene-1,4'-Piperidine] is a high-purity, advanced pharmaceutical intermediate with a complex spirocyclic structure. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of new therapeutic agents, particularly within central nervous system (CNS) and oncology drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and lead optimization.
• API Synthesis: Employed in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs), especially for neurological and oncological targets.
• Chemical Biology Probes: Serves as a starting material for developing tool compounds to study biological pathways and protein function.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Used in university and institutional labs for exploratory organic synthesis and heterocyclic chemistry studies.

Basic Information

Product Name	5-(Pyridin-3-Yl)-2,3-Dihydrospiro[Indene-1,4'-Piperidine]
CAS No.	1422057-78-0
Molecular Formula	C18H20N2
Molecular Weight	264.37 g/mol
Synonyms	5-(3-Pyridinyl)-2,3-dihydrospiro[1H-indene-1,4'-piperidine]; 5-(Pyridin-3-yl)-2,3-dihydro-1H-spiro[indene-1,4'-piperidine]; Spiro[indene-1,4'-piperidine], 5-(3-pyridinyl)-2,3-dihydro-; 1422057-78-0; 5-(3-Pyridyl)-2,3-dihydrospiro[indene-1,4'-piperidine]; 5-Pyridin-3-yl-2,3-dihydrospiro[indene-1,4'-piperidine]
EINECS	Contact for details

Quality Control

Our 5-(Pyridin-3-Yl)-2,3-Dihydrospiro[Indene-1,4'-Piperidine] is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and pre-clinical development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.