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Azido-Peg10-Azide CAS NO 1421783-42-7
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CAS No.:1421783-42-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Azido-Peg10-Azide is a heterobifunctional polyethylene glycol (PEG) linker featuring terminal azide groups. This compound is a critical reagent in bioconjugation and click chemistry, enabling the efficient, site-specific cross-linking of biomolecules and materials under mild, aqueous conditions. It is essential for researchers and manufacturers in pharmaceutical development, proteomics, and advanced material science who require precise and stable molecular assembly.
Application
- Bioconjugation and Antibody-Drug Conjugate (ADC) Development: Used as a linker to attach cytotoxic drugs, fluorophores, or other payloads to antibodies, proteins, or peptides.
- Click Chemistry Reactions: Serves as a key component in copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC) for labeling and polymer synthesis.
- PEGylation and Surface Modification: Imparts hydrophilicity, reduces immunogenicity, and extends circulation half-life when used to modify therapeutic proteins, nanoparticles, or biomedical surfaces.
- Hydrogel and Biomaterial Fabrication: Acts as a cross-linking agent to create biocompatible hydrogels for drug delivery systems, 3D cell culture, and tissue engineering scaffolds.
- Diagnostic Reagent Synthesis: Employed in the development of diagnostic assays, biosensors, and imaging probes by linking recognition elements to signal reporters.
- Polymer and Dendrimer Synthesis: Functions as a versatile building block for constructing functionalized polymers and dendritic structures with precise architecture.
Basic Information
| Item | Detail |
|---|---|
| Product Name | Azido-Peg10-Azide |
| CAS No. | 1421783-42-7 |
| Molecular Formula | C24H46N6O11 |
| Molecular Weight | 594.66 g/mol |
| Synonyms | 1-Azido-3,6,9,12,15,18,21,24,27,30-decaoxa-33-azapentatriacontan-35-azide; Bis-Azido-PEG10; α,ω-Diazido-PEG10; Azido-PEG10-Azide; PEG10 diazide; 1,11-Bis-azido-3,6,9-trioxaundecane (PEG10 analog); Azido-PEG-N3 (MW 600) |
| EINECS | Contact for details |
Quality Control
Our Azido-Peg10-Azide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance for sensitive research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. For long-term storage, keep the product under an inert atmosphere (e.g., argon or nitrogen) to prevent degradation. Keep away from heat and incompatible materials.
Specification
| Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow viscous liquid or oil |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 95% |
| Water Content (KF) | ≤ 1.0% |
| Average Molecular Weight | 590 - 600 g/mol |
| Functional Group Assay (Azide) | ≥ 90% of theoretical |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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