Description

(S)-1-tert-Butyl 3-Ethyl Pyrrolidine-1,3-Dicarboxylate is a high-purity chiral intermediate of significant importance in modern synthetic chemistry. This compound serves as a critical building block for the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of complex, stereochemically defined molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, particularly those targeting the central nervous system.
• Asymmetric Synthesis: Used as a precursor or auxiliary in catalytic asymmetric reactions to introduce stereogenic centers with high enantiomeric purity.
• Agrochemical Research: Employed in the development of new, enantiomerically pure pesticides and herbicides.
• Ligand and Catalyst Development: Serves as a starting material for the preparation of novel chiral ligands and organocatalysts.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis: A foundational component for contract research and manufacturing organizations (CROs/CMOs) offering bespoke chemical synthesis services.

Basic Information

Product Name	(S)-1-tert-Butyl 3-Ethyl Pyrrolidine-1,3-Dicarboxylate
CAS No.	1421256-03-2
Molecular Formula	C12H21NO4
Molecular Weight	243.30 g/mol
Synonyms	(S)-1-(tert-Butoxycarbonyl)-3-ethylpyrrolidine-3-carboxylic acid ethyl ester; (S)-1-Boc-3-ethylpyrrolidine-3-carboxylic acid ethyl ester; (S)-3-Ethyl-1-Boc-pyrrolidine-3-carboxylic acid ethyl ester; tert-Butyl (3S)-3-(ethoxycarbonyl)-3-ethylpyrrolidine-1-carboxylate; (S)-1-tert-Butyl 3-ethyl 3-ethylpyrrolidine-1,3-dicarboxylate; (S)-1-Boc-3-ethyl-3-(ethoxycarbonyl)pyrrolidine; Ethyl (3S)-1-(tert-butoxycarbonyl)-3-ethylpyrrolidine-3-carboxylate
EINECS	Contact for details

Quality Control

Our (S)-1-tert-Butyl 3-Ethyl Pyrrolidine-1,3-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity suitable for demanding research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.