Description

(7S)-7-Methyl-1,4-dioxa-8-azaspiro[4.5]decane is a high-purity, chiral spirocyclic building block of significant interest in advanced organic synthesis. This compound matters because it provides a rigid, three-dimensional scaffold that is crucial for modulating the physicochemical and biological properties of complex molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly where stereochemistry is a critical factor for efficacy.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of central nervous system (CNS) active drugs, protease inhibitors, and other therapeutic agents requiring precise stereochemical control.
• Agrochemical Research: Used in the synthesis of novel, stereochemically-defined pesticides and herbicides to enhance target specificity and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Exploration of its use in creating novel polymers and functional materials with specific chiral or structural properties.
• Academic & Contract Research: A valuable tool for methodological development in organic chemistry and for creating compound libraries for high-throughput screening.

Basic Information

Product Name	(7S)-7-Methyl-1,4-dioxa-8-azaspiro[4.5]decane
CAS No.	1419140-80-9
Molecular Formula	C9H17NO2
Molecular Weight	171.24 g/mol
Synonyms	(7S)-7-Methyl-1,4-dioxa-8-azaspiro[4.5]decane; (S)-7-Methyl-1,4-dioxa-8-azaspiro[4.5]decane; 8-Azaspiro[4.5]decane, 7-methyl-, (7S)-, 1,4-dioxa-; (7S)-7-Methyl-1,4-dioxa-8-azaspiro[4.5]decane; Spirocyclic morpholine derivative; Chiral spirocyclic ether-amine
EINECS	Contact for details

Quality Control

Our (7S)-7-Methyl-1,4-dioxa-8-azaspiro[4.5]decane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request, supporting compliance with research and cGMP standards for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.