Description

5-Aza-Spiro[3.5]Nonane Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic amine structure. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of novel drug candidates. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of small molecule therapeutics, particularly for central nervous system (CNS) and metabolic disease targets.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its constrained spirocyclic scaffold.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or component in the design of bifunctional degrader molecules.
• Chemical Biology Probes: Utilized in the creation of tool compounds for studying enzyme function and biological pathways.
• Agrochemical Research: Investigated as an intermediate for developing new active ingredients with novel modes of action.
• Academic Synthesis: Employed in methodological development and the study of spirocyclic compound chemistry.

Basic Information

Product Name	5-Aza-Spiro[3.5]Nonane Hydrochloride
CAS No.	1419101-47-5
Molecular Formula	C8H15ClN2
Molecular Weight	174.67 g/mol
Synonyms	5-Azaspiro[3.5]nonane hydrochloride; 1-Azaspiro[3.5]nonane hydrochloride; 5-Aza-spiro[3.5]nonane HCl; 5-Azaspiro[3.5]nonane, hydrochloride; 5-Aza-spiro[3.5]nonane monohydrochloride; Azaspiro[3.5]nonane hydrochloride; Spiro[cyclopropane-1,4'-piperidine] hydrochloride
EINECS	Contact for details

Quality Control

Our 5-Aza-Spiro[3.5]Nonane Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.