Description

6,6-Difluoro-Spiro[3.3]heptane-2-carboxylic acid is a high-value, multifunctional fluorinated building block characterized by its unique spirocyclic and difluoromethylene architecture. This compound is essential for medicinal chemistry and advanced materials research, where its rigid, three-dimensional structure and fluorine atoms are leveraged to modulate the physicochemical properties of target molecules. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the discovery and development of new drug candidates, particularly for central nervous system (CNS) and metabolic disease targets.
• Agrochemical Synthesis: Used to create novel, potent active ingredients with improved stability and bioavailability for crop protection products.
• Material Science: Serves as a precursor for specialty polymers, liquid crystals, and advanced organic frameworks where fluorine incorporation enhances thermal and chemical stability.
• Fluorine Chemistry Research: An important reagent for exploring new fluorination methodologies and the construction of complex, fluorinated molecular architectures in academic and industrial R&D.
• PET Tracer Development: Potential utility as a building block for Positron Emission Tomography (PET) imaging agents due to the presence of fluorine atoms.

Basic Information

Product Name	6,6-Difluoro-Spiro[3.3]heptane-2-carboxylic Acid
CAS No.	1419101-45-3
Molecular Formula	C9H10F2O2
Molecular Weight	188.17 g/mol
Synonyms	6,6-Difluorospiro[3.3]heptane-2-carboxylic acid; 2-Carboxy-6,6-difluorospiro[3.3]heptane; 6,6-Difluoro-2-spiro[3.3]heptanecarboxylic acid; 1419101-45-3; Difluoro-spiroheptane carboxylic acid; 6,6-Difluoro-2-carboxyspiro[3.3]heptane; Spiro[3.3]heptane-2-carboxylic acid, 6,6-difluoro-
EINECS	Contact for details

Quality Control

Our 6,6-Difluoro-Spiro[3.3]heptane-2-carboxylic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.