Description

6-Cbz-1-Hydroxy-6-Aza-Spiro[3.4]Octane CAS NO 1419101-06-6 is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of novel drug candidates. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within the fields of central nervous system (CNS) and metabolic disease research.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex, biologically active molecules and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies to develop new drug candidates.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or component in the design of bifunctional degrader molecules.
• CNS Drug Discovery: The spiro[3.4]octane core is valuable for creating novel compounds targeting neurological disorders.
• Chemical Biology Probes: Utilized in the creation of tool compounds for studying biological pathways and target validation.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthetic routes for clients.

Basic Information

Product Name	6-Cbz-1-Hydroxy-6-Aza-Spiro[3.4]Octane
CAS No.	1419101-06-6
Molecular Formula	C₁₅H₁₉NO₃
Molecular Weight	261.32 g/mol
Synonyms	1-[(Benzyloxy)carbonyl]-6-hydroxy-6-azaspiro[3.4]octane; 6-(Benzyloxycarbonyl)-6-azaspiro[3.4]octan-1-ol; 6-Azaspiro[3.4]octan-1-ol, 6-[(phenylmethoxy)carbonyl]-; 6-Cbz-6-azaspiro[3.4]octan-1-ol; Benzyl 1-hydroxy-6-azaspiro[3.4]octane-6-carboxylate; 6-Cbz-1-OH-6-Aza-Spiro[3.4]Octane
EINECS	Contact for details

Quality Control

Every batch of 6-Cbz-1-Hydroxy-6-Aza-Spiro[3.4]Octane is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.