Description

(7R)-7-Methyl-1,4-Dioxa-8-Azaspiro[4.5]Decane is a high-value, chiral spirocyclic building block of significant interest in advanced organic synthesis. Its rigid, three-dimensional structure and heteroatom functionality make it a critical intermediate for constructing complex molecular architectures with precise stereochemistry. This compound is primarily sought after by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, where it serves as a key scaffold for protease inhibitors, receptor modulators, and other biologically active molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) agents and antiviral therapies.
• Agrochemical Synthesis: Used in the creation of advanced, stereospecific pesticides and herbicides with improved efficacy and environmental profiles.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands and organocatalysts.
• Chemical Biology & Proteomics: Employed in the design of activity-based probes and molecular tools for studying enzyme function.
• Material Science Research: Investigated as a monomer or additive for creating polymers with unique thermal or mechanical properties.
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	(7R)-7-Methyl-1,4-Dioxa-8-Azaspiro[4.5]Decane
CAS No.	1419075-94-7
Molecular Formula	C9H17NO2
Molecular Weight	171.24 g/mol
Synonyms	(7R)-7-Methyl-1,4-dioxa-8-azaspiro[4.5]decane; 8-Azaspiro[4.5]decane, 7-methyl-, (7R)-, 1,4-dioxa-; (R)-7-Methyl-1,4-dioxa-8-azaspiro[4.5]decane; 1,4-Dioxa-8-azaspiro[4.5]decane, 7-methyl-, (7R)-; (7R)-7-Methyl-1,4-dioxa-8-azaspiro[4,5]decane; Chiral Spirocyclic Amine Ether; (R)-form of 7-Methyl-1,4-dioxa-8-azaspiro[4.5]decane
EINECS	Contact for details

Quality Control

Every batch of (7R)-7-Methyl-1,4-Dioxa-8-Azaspiro[4.5]Decane is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure the identity, purity, and enantiomeric excess meet the exacting standards required for pharmaceutical and advanced synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as assay, chiral purity (enantiomeric excess), and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.