Description

4-(Trimethylsilyl)Phenyl Pivalate is a specialized organosilicon ester compound, identified by CAS NO 1418117-88-0. This chemical serves as a valuable protected phenol intermediate and a versatile silylating agent in advanced organic synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly where phenol protection is required.
• Advanced Material Synthesis: Used in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Agrochemical Research: Serves as a precursor in the design and synthesis of novel crop protection agents.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki-Miyaura and other palladium-catalyzed coupling reactions.
• Organic Synthesis Reagent: Employed as a silylating agent to introduce the trimethylsilyl group, modifying solubility and reactivity.
• Chemical Derivatization: Useful for analytical chemistry applications, such as preparing derivatives for GC-MS analysis.

Basic Information

Product Name	4-(Trimethylsilyl)Phenyl Pivalate
CAS No.	1418117-88-0
Molecular Formula	C14H22O2Si
Molecular Weight	250.41 g/mol
Synonyms	Pivalic Acid 4-(Trimethylsilyl)Phenyl Ester; 4-(Trimethylsilyl)phenyl 2,2-dimethylpropanoate; 4-TMS-Phenyl Pivalate; Trimethyl(4-(pivaloyloxy)phenyl)silane; 4-(Trimethylsilyl)phenol Pivalate Ester; 4-Hydroxyphenyltrimethylsilane Pivalate; Pivaloyloxyphenyltrimethylsilane
EINECS	Contact for details

Quality Control

Our 4-(Trimethylsilyl)Phenyl Pivalate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. Certificates of Analysis (COA) are provided, detailing purity, identity, and impurity profiles as confirmed by HPLC, GC, NMR, and IR spectroscopy. We are committed to meeting the stringent requirements of research and cGMP-grade applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.