Description

4-[(3-Chloro-5-Trifluoromethyl-Pyridin-2-Yl)-Methyl-Amino]-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-value, advanced pharmaceutical intermediate featuring a piperidine core with a substituted pyridine moiety. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of complex small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel compounds.
• API Synthesis: Serves as a crucial precursor in the multi-step synthesis of final active pharmaceutical ingredients.
• Chemical Biology: Employed in the development of chemical probes and tool compounds for biological target validation.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke molecules for clients.
• Agrochemical Research: Potential intermediate in the development of advanced crop protection agents, leveraging its heterocyclic structure.

Basic Information

Product Name	4-[(3-Chloro-5-Trifluoromethyl-Pyridin-2-Yl)-Methyl-Amino]-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1417793-99-7
Molecular Formula	C18H23ClF3N3O2
Molecular Weight	405.84 g/mol
Synonyms	tert-Butyl 4-[[(3-chloro-5-(trifluoromethyl)pyridin-2-yl)methyl]amino]piperidine-1-carboxylate; 1-Boc-4-[[(3-chloro-5-(trifluoromethyl)-2-pyridinyl)methyl]amino]piperidine; 4-[(3-Chloro-5-trifluoromethyl-pyridin-2-yl)-methyl-amino]-piperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-[[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]methyl]amino]piperidine; BOC-4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methylamino)piperidine; CAS 1417793-99-7
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive R&D and scale-up applications. Certificates of Analysis (COA) are provided with each shipment, detailing purity, identity, and impurity profiles. Quality systems are designed to support development under cGMP guidelines where required, ensuring suitability for use in regulated pharmaceutical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.