Description

5-Bromo-2-(Piperidin-4-Ylmethoxy)-Pyridine Hydrochloride is a high-purity organic building block and pharmaceutical intermediate of significant commercial interest. Its molecular structure, featuring a brominated pyridine core linked to a piperidine moiety, makes it a valuable scaffold for medicinal chemistry research and drug discovery programs. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used as a versatile building block for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes to study biological pathways and protein function.
• Process Chemistry & Scale-Up: Provides a defined starting material for optimizing synthetic routes and scaling up candidate molecules from milligram to kilogram quantities.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the life sciences industry.

Basic Information

Product Name	5-Bromo-2-(Piperidin-4-Ylmethoxy)-Pyridine Hydrochloride
CAS No.	1417793-67-9
Molecular Formula	C11H16BrClN2O
Molecular Weight	307.62 g/mol
Synonyms	5-Bromo-2-[(4-piperidinyl)methoxy]pyridine hydrochloride; 2-[(Piperidin-4-yl)methoxy]-5-bromopyridine hydrochloride; 5-Bromo-2-(piperidin-4-ylmethoxy)pyridine HCl; 1417793-67-9; 5-Bromo-2-(4-piperidylmethoxy)pyridine hydrochloride
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(Piperidin-4-Ylmethoxy)-Pyridine Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.