Description

(5'-Bromo-3,4,5,6-Tetrahydro-2H-[1,2']Bipyridinyl-3-Yl)-Carbamic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate designed for complex synthesis pathways. This compound matters for its role as a critical building block in the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily needed by R&D chemists and process development scientists in pharmaceutical, biotechnology, and fine chemical industries seeking to streamline the synthesis of complex nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially those targeting neurological disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Process Chemistry Development: Serves as a standardized building block for scaling up synthetic routes under current Good Manufacturing Practice (cGMP) conditions.
• Ligand and Catalyst Synthesis: Employed in the preparation of complex nitrogen-based ligands for catalytic applications.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis Projects: A starting material for contract research organizations (CROs) and custom synthesis providers working on proprietary compounds.

Basic Information

Product Name	(5'-Bromo-3,4,5,6-Tetrahydro-2H-[1,2']Bipyridinyl-3-Yl)-Carbamic Acid tert-Butyl Ester
CAS No.	1417793-65-7
Molecular Formula	C15H22BrN3O2
Molecular Weight	356.26 g/mol
Synonyms	tert-Butyl N-(5'-bromo-3,4,5,6-tetrahydro-2H-[1,2'-bipyridin]-3-yl)carbamate; (5'-Bromo-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-3-yl)carbamic acid 1,1-dimethylethyl ester; BOC-Protected 5'-Bromo-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-3-amine; 5'-Bromo-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-3-yl-carbamic acid tert-butyl ester; N-Boc-5'-bromo-1,2,3,4-tetrahydro-[2,2'-bipyridin]-3-amine
EINECS	Contact for details

Quality Control

Our (5'-Bromo-3,4,5,6-Tetrahydro-2H-[1,2']Bipyridinyl-3-Yl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.