Description

16-Oxoestradiol is a key steroidal intermediate and metabolite of estradiol, distinguished by the introduction of a ketone group at the C16 position. This structural modification makes it a valuable compound for biochemical research and pharmaceutical development, particularly in the study of estrogen metabolism and hormone-related pathways. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors who require high-purity reference standards and synthetic building blocks.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for analytical method development and validation in drug testing and quality control laboratories.
• Biochemical Research: Serves as a critical metabolite in studies investigating estrogen biosynthesis, catabolism, and related endocrine signaling pathways.
• Active Pharmaceutical Ingredient (API) Intermediate: Acts as a key synthetic precursor in the production of more complex steroidal drugs and novel therapeutic agents.
• Diagnostic Reagent Manufacturing: Utilized in the development and calibration of diagnostic kits and assays for hormonal analysis.
• Academic & Institutional Research: Employed in universities and research institutes for fundamental studies in steroid chemistry and endocrinology.

Basic Information

Product Name	16-Oxoestradiol
CAS No.	1417721-33-5
Molecular Formula	C18H22O3
Molecular Weight	286.36 g/mol
Synonyms	Estra-1,3,5(10)-triene-3,16α,17β-triol-16-one; 16-Oxoestra-1,3,5(10)-triene-3,17β-diol; 16-Ketoestradiol; 16-Oxo-E2; 16-Oxo-17β-estradiol
EINECS	Contact for details

Quality Control

Our 16-Oxoestradiol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and reliability for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.