Description

2,8-Diazaspiro[4.5]Decan-3-One Dihydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within the fields of central nervous system (CNS) and metabolic disorder research.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its spirocyclic structure, which can impart favorable pharmacokinetic properties.
• API Development: Serves as a critical precursor in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for exploratory chemistry and the development of new synthetic methodologies involving nitrogen-containing heterocycles.

Basic Information

Product Name	2,8-Diazaspiro[4.5]Decan-3-One Dihydrochloride
CAS No.	1417301-86-0
Molecular Formula	C8H16N2O • 2HCl
Molecular Weight	237.14 g/mol (for dihydrochloride salt)
Synonyms	2,8-Diazaspiro[4.5]decan-3-one dihydrochloride; 3-Oxo-2,8-diazaspiro[4.5]decane dihydrochloride; 2,8-Diazaspiro[4.5]decan-3-one hydrochloride (1:2); 2,8-Diazaspiro[4.5]decan-3-one, hydrochloride; Spiro[4.5]decane-8,2'-imidazolidine]-3'-one dihydrochloride
EINECS	Contact for details

Quality Control

Our 2,8-Diazaspiro[4.5]Decan-3-One Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a Certificate of Analysis (COA) with every shipment to ensure full traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.