Description

2,6-Piperidinedione, 3-(1,3-Dihydro-7-Hydroxy-1-Oxo-2H-Isoindol-2-Yl)- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of complex drug candidates, especially those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and the discovery of new bioactive molecules.
• API Development: Integral to the process development and scale-up of new Active Pharmaceutical Ingredients (APIs) requiring its specific fused-ring piperidinedione core.
• Contract Manufacturing (CMO): Supplied to Contract Manufacturing Organizations for the production of clinical trial materials and commercial drug substances.
• Biochemical Research: May be employed as a tool compound or inhibitor in biochemical assays to study specific enzymatic or cellular processes.
• Fine Chemical Synthesis: Used in the synthesis of other specialized, high-value fine chemicals and complex organic molecules.

Basic Information

Product Name	2,6-Piperidinedione, 3-(1,3-Dihydro-7-Hydroxy-1-Oxo-2H-Isoindol-2-Yl)-
CAS No.	1416990-10-7
Molecular Formula	C13H12N2O4
Molecular Weight	260.25 g/mol
Synonyms	3-(1,3-Dihydro-7-hydroxy-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione; 3-(7-Hydroxy-1-oxoisoindolin-2-yl)piperidine-2,6-dione; 2,6-Piperidinedione, 3-(1,3-dihydro-7-hydroxy-1-oxo-2H-isoindol-2-yl)-; 1416990-10-7; 7-Hydroxy-2-(2,6-dioxopiperidin-3-yl)isoindolin-1-one
EINECS	Contact for details

Quality Control

Our 2,6-Piperidinedione, 3-(1,3-Dihydro-7-Hydroxy-1-Oxo-2H-Isoindol-2-Yl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.