Description

1,5-Naphthyridine, 8-Bromo-7-Fluoro-2-Methyl- is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique halogenated naphthyridine structure, which serves as a critical scaffold for constructing complex molecules with tailored properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Research: Used to develop novel active ingredients for crop protection products, leveraging its halogenated heterocyclic core.
• Material Science: Serves as a building block for creating organic semiconductors, ligands for metal-organic frameworks (MOFs), and specialty polymers.
• Chemical Biology: Employed as a molecular probe or a fluorescent tag precursor due to the naphthyridine scaffold's potential photophysical properties.
• Academic & Contract Research: Utilized in universities and CROs for methodological development and exploring new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	1,5-Naphthyridine, 8-Bromo-7-Fluoro-2-Methyl-
CAS No.	1416373-76-6
Molecular Formula	C9H6BrFN2
Molecular Weight	241.06 g/mol
Synonyms	8-Bromo-7-fluoro-2-methyl-1,5-naphthyridine; 2-Methyl-8-bromo-7-fluoro-1,5-naphthyridine; 1,5-Naphthyridine, 8-bromo-7-fluoro-2-methyl-; 1416373-76-6; 8-Bromo-7-fluoro-2-methyl-[1,5]naphthyridine; 7-Fluoro-8-bromo-2-methyl-1,5-naphthyridine; Bromo-fluoro-methylnaphthyridine
EINECS	Contact for details

Quality Control

Our 1,5-Naphthyridine, 8-Bromo-7-Fluoro-2-Methyl- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.