Description

2-Oxa-5,8-Diaza-Spiro[3.5]Nonanedihydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system and metabolic disorders. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel active pharmaceutical ingredients (APIs) with spirocyclic architectures.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore new chemical space and improve drug-like properties.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a component for constructing linkers or warheads in bifunctional degrader molecules.
• Chemical Biology Probes: Employed in the creation of tool compounds for target validation and pathway analysis in biological systems.
• Library Synthesis for High-Throughput Screening: A valuable scaffold for generating diverse compound libraries to identify new biological activities.
• Academic Research: Used in universities and research institutes for studies in synthetic methodology and heterocyclic chemistry.

Basic Information

Product Name	2-Oxa-5,8-Diaza-Spiro[3.5]Nonanedihydrochloride
CAS No.	1416323-26-6
Molecular Formula	C6H12Cl2N2O
Molecular Weight	199.08 g/mol
Synonyms	2-Oxa-5,8-diaza-spiro[3.5]nonane dihydrochloride; 5,8-Diaza-2-oxaspiro[3.5]nonane dihydrochloride; Spiro[3.5]nonane-2-oxa-5,8-diaza dihydrochloride; 2-Oxa-5,8-diazaspiro[3.5]nonane hydrochloride (1:2); 1416323-26-6; 2-Oxa-5,8-diazaspiro[3.5]nonane dihydrochloride
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and pharmaceutical development. Each batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.