Description

1H-Pyrrole-2-Carboxylic Acid, 4-(2-Chloroacetyl)-, Methyl Ester is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its bifunctional molecular architecture, featuring both a reactive pyrrole core and a chloroacetyl ester moiety, making it a versatile precursor for constructing complex pharmacophores. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and plant growth regulators that require complex heterocyclic scaffolds.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of advanced polymers, conductive materials, and organic electronic components.
• Chemical Biology & Proteomics: Employed as a reactive handle for bioconjugation, labeling biomolecules, or creating activity-based probes for enzyme studies.
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry and for exploring new chemical spaces in discovery programs.

Basic Information

Item	Details
Product Name	1H-Pyrrole-2-Carboxylic Acid, 4-(2-Chloroacetyl)-, Methyl Ester
CAS No.	1415820-00-6
Molecular Formula	C8H8ClNO3
Molecular Weight	201.61 g/mol
Synonyms	Methyl 4-(2-chloroacetyl)-1H-pyrrole-2-carboxylate; 4-(Chloroacetyl)-1H-pyrrole-2-carboxylic acid methyl ester; 1H-Pyrrole-2-carboxylic acid, 4-(chloroacetyl)-, methyl ester; Methyl 4-(chloroacetyl)pyrrole-2-carboxylate; 4-(2-Chloroacetyl)-1H-pyrrole-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrrole-2-Carboxylic Acid, 4-(2-Chloroacetyl)-, Methyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.