Description

2-Benzyl-2,5-Diazaspiro[3.4]Octane-5-Carboxylic Acid 1,1-Dimethylethyl Ester is a high-value, advanced pharmaceutical intermediate featuring a unique spirocyclic diaza scaffold. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel bioactive molecules targeting central nervous system and other therapeutic areas. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of innovative active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those with spirocyclic or constrained ring systems.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for developing new therapeutic agents.
• CNS Drug Development: Serves as a precursor for compounds targeting neurological disorders, leveraging the diazaspiro[3.4]octane core.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs (Contract Development and Manufacturing Organizations) for the scalable production of client-specific molecules.
• Chemical Biology Probes: Utilized in the creation of specialized molecular tools for studying biological pathways and protein interactions.
• Library Synthesis for High-Throughput Screening: A valuable scaffold for generating diverse compound libraries to identify new hits in drug discovery campaigns.

Basic Information

Product Name	2-Benzyl-2,5-Diazaspiro[3.4]Octane-5-Carboxylic Acid 1,1-Dimethylethyl Ester
CAS No.	1415562-45-6
Molecular Formula	C19H28N2O2
Molecular Weight	316.44 g/mol
Synonyms	tert-Butyl 2-benzyl-2,5-diazaspiro[3.4]octane-5-carboxylate; 2,5-Diazaspiro[3.4]octane-5-carboxylic acid, 2-(phenylmethyl)-, 1,1-dimethylethyl ester; 2-Benzyl-2,5-diazaspiro[3.4]octane-5-carboxylic acid tert-butyl ester; 2-Benzyl-N-Boc-2,5-diazaspiro[3.4]octane; Boc-2-benzyl-2,5-diazaspiro[3.4]octane
EINECS	Contact for details

Quality Control

Our production of 2-Benzyl-2,5-Diazaspiro[3.4]Octane-5-Carboxylic Acid 1,1-Dimethylethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We operate under a quality system designed to meet the expectations of pharmaceutical development partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.