Description

6-Amino-2-Aza-Spiro[3.3]Heptane-2-Carboxylic Acid tert-Butyl Ester Hydrochloride is a high-value, protected amino acid derivative featuring a rigid spirocyclic scaffold. This compound is a critical pharmaceutical intermediate and building block for medicinal chemistry, enabling the synthesis of novel drug candidates with constrained geometries. It is primarily utilized by R&D and production teams in the pharmaceutical, biotechnology, and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel small molecule therapeutics, particularly in protease inhibitor and central nervous system (CNS) drug discovery.
• Peptidomimetics & Constrained Peptides: Used to introduce conformational rigidity into peptide backbones, enhancing metabolic stability and target binding affinity.
• Chemical Biology Probes: Serves as a scaffold for developing tool compounds and probes to study biological pathways and protein function.
• Agrochemical Research: Employed in the discovery of new crop protection agents and pesticides with novel modes of action.
• Academic & Contract Research: Essential for academic research and contract research organizations (CROs) focused on synthetic methodology and new chemical entity development.

Basic Information

Product Name	6-Amino-2-Aza-Spiro[3.3]Heptane-2-Carboxylic Acid tert-Butyl Ester Hydrochloride
CAS No.	1414958-13-6
Molecular Formula	C11H21ClN2O2
Molecular Weight	248.75 g/mol
Synonyms	tert-Butyl 6-amino-2-azaspiro[3.3]heptane-2-carboxylate hydrochloride; 2-Azaspiro[3.3]heptane-2-carboxylic acid, 6-amino-, 1,1-dimethylethyl ester, hydrochloride; 6-Amino-2-azaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester HCl; 2-Aza-spiro[3.3]heptane-6-amine, 2-(tert-butoxycarbonyl)-, hydrochloride; Boc-6-Amino-2-aza-spiro[3.3]heptane hydrochloride; (6-Amino-2-azaspiro[3.3]hept-2-yl)-tert-butylcarboxylate hydrochloride
EINECS	Contact for details

Quality Control

Our 6-Amino-2-Aza-Spiro[3.3]Heptane-2-Carboxylic Acid tert-Butyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.