Description

7-Aza-Spiro[3.5]Nonane Hydrochloride is a high-value, nitrogen-containing spirocyclic building block essential for modern pharmaceutical and agrochemical research. Its unique constrained spirocyclic scaffold provides a versatile platform for constructing complex molecular architectures with potential biological activity. This compound is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical industry for drug discovery programs targeting central nervous system disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for neurological and psychiatric targets.
• Medicinal Chemistry: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its three-dimensional, shape-diverse properties.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening (HTS) against various biological targets.
• Agrochemical Research: Serves as a precursor in the development of new crop protection agents and pesticides.
• Chemical Biology: Useful as a probe or tool compound for studying enzyme mechanisms or protein-ligand interactions.
• Process Chemistry: Investigated for scalable synthetic routes in the development of cost-effective manufacturing processes for advanced intermediates.

Basic Information

Product Name	7-Aza-Spiro[3.5]Nonane Hydrochloride
CAS No.	1414885-16-7
Molecular Formula	C8H16ClN
Molecular Weight	161.67 g/mol
Synonyms	7-Azaspiro[3.5]nonane hydrochloride; 7-Aza-spiro[3.5]nonane HCl; 1-Azaspiro[3.5]nonane hydrochloride; Azaspiro[3.5]nonane hydrochloride; 7-Aza-spiro[3,5]nonane hydrochloride; 7-Aza-spiro(3.5)nonane hydrochloride; 7-Aza-spiro[3.5]nonane, hydrochloride
EINECS	Contact for details

Quality Control

Our 7-Aza-Spiro[3.5]Nonane Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability and traceability for your critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.