Description

6-Phenyl-2-Oxa-Spiro[3.3]heptane-6-carbonitrile is a high-value, spirocyclic organic building block featuring a unique oxa-spiro[3.3]heptane core. This compound is of significant interest in advanced pharmaceutical and agrochemical research, serving as a versatile intermediate for constructing complex molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and life sciences industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in programs targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the synthesis of new-generation herbicides and fungicides, leveraging its spirocyclic structure for enhanced biological activity and environmental profile.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Investigated as a monomer or cross-linking agent for creating polymers with specific thermal or mechanical properties.
• Chemical Biology Probe Synthesis: Utilized to build molecular probes for studying enzyme function and cellular pathways.

Basic Information

Product Name	6-Phenyl-2-Oxa-Spiro[3.3]heptane-6-Carbonitrile
CAS No.	1414513-75-9
Molecular Formula	C14H13NO
Molecular Weight	211.26 g/mol
Synonyms	6-Phenyl-2-oxaspiro[3.3]heptane-6-carbonitrile; 2-Oxa-6-phenylspiro[3.3]heptane-6-carbonitrile; 6-Cyano-6-phenyl-2-oxaspiro[3.3]heptane; 6-Phenyl-6-cyano-2-oxaspiro[3.3]heptane; 1414513-75-9; Spiro[2.4]heptane-6-carbonitrile, 1-phenyl-5-oxa- (related structural name)
EINECS	Contact for details

Quality Control

Our production of 6-Phenyl-2-Oxa-Spiro[3.3]heptane-6-Carbonitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, and NMR, for comprehensive identity confirmation and impurity profiling. A Certificate of Analysis (COA) detailing purity, assay, and specific tests is provided with each shipment. Our quality system is designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for long-term storage. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.