Description

8-Oxa-2,6-Diaza-Spiro[4.5]-Decan-7-One Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral research. It is essential for medicinal chemistry R&D and process development teams in the pharmaceutical and biotechnology industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting neurological disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• Process Chemistry Development: Serves as a starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Bioconjugation & Probe Development: The reactive functional groups can be utilized for creating biochemical probes and targeted conjugates.
• Academic & Institutional Research: Employed in universities and research institutes for studying spirocyclic compound chemistry and pharmacology.

Basic Information

Product Name	8-Oxa-2,6-Diaza-Spiro[4.5]-Decan-7-One Hydrochloride
CAS No.	1408076-26-5
Molecular Formula	C7H12ClN3O2
Molecular Weight	205.64 g/mol
Synonyms	8-Oxa-2,6-diazaspiro[4.5]decan-7-one hydrochloride; 7-Oxo-8-oxa-2,6-diazaspiro[4.5]decane hydrochloride; 2,6-Diaza-8-oxaspiro[4.5]decan-7-one HCl; Spiro[4.5]decan-7-one, 8-oxa-2,6-diaza-, hydrochloride; 1408076-26-5; 8-Oxa-2,6-diaza-spiro[4.5]decan-7-one HCl
EINECS	Contact for details

Quality Control

Our 8-Oxa-2,6-Diaza-Spiro[4.5]-Decan-7-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.