Description

7-Boc-1-Oxa-3-Oxo-7-Azaspiro[3.5]Nonane is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic oxazolidinone scaffold. This compound is a critical building block in modern medicinal chemistry, valued for its role in constructing complex molecular architectures with potential biological activity. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective therapeutics.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel spirocyclic compounds with potential therapeutic applications.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore new chemical space and improve drug-like properties.
• Protease Inhibitor Development: Serves as a core scaffold in the design and synthesis of inhibitors for various enzymatic targets.
• Chemical Biology Probes: Utilized in the creation of tool compounds for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: A starting material for the custom production of complex molecules under cGMP or research-grade conditions.
• Academic Research: Employed in universities and institutes for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	7-Boc-1-Oxa-3-Oxo-7-Azaspiro[3.5]Nonane
CAS No.	1408076-15-2
Molecular Formula	C11H17NO5
Molecular Weight	243.26 g/mol
Synonyms	1-Oxa-3-oxo-7-[(2-methylpropan-2-yl)oxycarbonyl]-7-azaspiro[3.5]nonane; 7-(tert-Butoxycarbonyl)-1-oxa-3-oxo-7-azaspiro[3.5]nonane; tert-Butyl 1-oxa-3-oxo-7-azaspiro[3.5]nonane-7-carboxylate; 7-Boc-1-oxa-3-oxa-7-azaspiro[3.5]nonane; BOC-protected spirocyclic oxazolidinone; Spiro[3.5]nonane-7-carboxylic acid, 1-oxa-3-oxo-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 7-Boc-1-Oxa-3-Oxo-7-Azaspiro[3.5]Nonane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can be aligned with research-grade or cGMP standards based on customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.