Description

6-Benzyl-8-Oxa-2,6-Diaza-Spiro[4.5]Decan-7-One Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its complex spirocyclic structure. This compound is of significant value for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents. It is primarily sought by pharmaceutical companies and contract research organizations (CROs) engaged in the development of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting neurological and metabolic disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new pharmacophores.
• API Synthesis: Serves as a critical precursor in multi-step synthetic routes for the production of potential Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target validation.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) specializing in bespoke, small-scale synthesis for clinical trials.

Basic Information

Product Name	6-Benzyl-8-Oxa-2,6-Diaza-Spiro[4.5]Decan-7-One Hydrochloride
CAS No.	1408075-72-8
Molecular Formula	C15H19N3O2•HCl
Molecular Weight	309.79 g/mol (Free base: 273.33 g/mol)
Synonyms	6-Benzyl-8-oxa-2,6-diazaspiro[4.5]decan-7-one hydrochloride; 8-Oxa-2,6-diazaspiro[4.5]decan-7-one, 6-benzyl-, hydrochloride; 6-Benzyl-8-oxa-2,6-diazaspiro[4.5]decan-7-one HCl; 1408075-72-8; UNII-9Q3J7C1F5I; 9Q3J7C1F5I; Spiro[4.5]decan-7-one, 6-benzyl-8-oxa-2,6-diaza-, hydrochloride
EINECS	Contact for details

Quality Control

Our 6-Benzyl-8-Oxa-2,6-Diaza-Spiro[4.5]Decan-7-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with exacting standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.